The TLE1 Polyclonal Antibody (CAB13360) is a valuable tool for researchers studying TLE1, a transcriptional corepressor involved in various cellular processes, including development, differentiation, and proliferation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot applications.TLE1 is a key player in the regulation of gene expression and has been implicated in numerous diseases, including cancer. By targeting TLE1, researchers can gain insights into the mechanisms of cancer development and progression, potentially leading to the development of novel therapeutic strategies.
With its ability to detect and analyze TLE1 in a variety of cell types, the TLE1 Polyclonal Antibody is a valuable tool for investigators in the fields of oncology, developmental biology, and regenerative medicine. Its applications in research make it an essential reagent for studies aimed at understanding the role of TLE1 in health and disease.
Product Name:
TLE1 Rabbit Polyclonal Antibody
SKU:
CAB13360
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 256-355 of human TLE1 (NP_005068.2).
Enables identical protein binding activity and transcription corepressor activity. Involved in negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of anoikis; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex.
Purification Method:
Affinity purification
Gene ID:
7088
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse liver, using TLE1 Rabbit pAb (CAB13360) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
