The TKTL2 Polyclonal Antibody (PAC041050) is a valuable tool for researchers studying the TKTL2 protein, a key player in the pentose phosphate pathway and cancer metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TKTL2 protein, researchers can effectively detect and analyze this protein in various cell types, making it an essential tool for studies in cancer biology and metabolism research.
TKTL2 is an enzyme involved in glucose metabolism that has been implicated in promoting tumor growth and metastasis. Its role in cancer cell proliferation and survival makes it a promising target for the development of novel cancer therapies. By understanding the function and regulation of TKTL2, researchers can uncover new insights into cancer biology and potentially identify new treatment strategies to combat cancer progression.
Antibody Name:
TKTL2 Antibody (PACO41050)
Antibody SKU:
PACO41050
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Transketolase-like protein 2 protein (1-300AA)
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO41050 at dilution of 1:100.
Background:
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.
Synonyms:
Transketolase-like protein 2 (EC 2.2.1.1), TKTL2
UniProt Protein Function:
TKTL2: Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. Belongs to the transketolase family.Protein type: Transferase; Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.1Chromosomal Location of Human Ortholog: 4q32.2Cellular Component: cytoplasm
