Thymidine Kinase 1 Rabbit Polyclonal Antibody (CAB5612)
- SKU:
- CAB5612
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Thymidine Kinase 1 Rabbit Polyclonal Antibody |
SKU: | CAB5612 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-194 of human Thymidine Kinase 1 (NP_003249.3). |
Sequence: | SKTR GQIQ VILG PMFS GKST ELMR RVRR FQIA QYKC LVIK YAKD TRYS SSFC THDR NTME ALPA CLLR DVAQ EALG VAVI GIDE GQFF PDIV EFCE AMAN AGKT VIVA ALDG TFQR KPFG AILN LVPL AESV VKLT AVCM ECFR EAAY TKRL GTEK EVEV IGGA DKYH SVCR LCYF KKAS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | TK2; Thymidine Kinase 1 |
Positive Sample: | HeLa,293T,Jurkat,Mouse liver,Mouse spleen,Mouse stomach,Rat liver,Rat spleen,Rat stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 25kDa |
Observed MW: | 26kDa |
The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.
Purification Method: | Affinity purification |
Gene ID: | 7083 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |