TJP2 Rabbit Polyclonal Antibody (CAB0594)
- SKU:
- CAB0594
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TJP2 Rabbit Polyclonal Antibody |
SKU: | CAB0594 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 951-1190 of human TJP2 (NP_004808.2). |
Sequence: | RSSE PVQH EESI RKPS PEPR AQMR RAAS SDQL RDNS PPPA FKPE PPKA KTQN KEES YDFS KSYE YKSN PSAV AGNE TPGA STKG YPPP VAAK PTFG RSIL KPST PIPP QEGE EVGE SSEE QDNA PKSV LGKV KIFE KMDH KARL QRMQ ELQE AQNA RIEI AQKH PDIY AVPI KTHK PDPG TPQH TSSR PPEP QKAP SRPY QDTR GSYG SDAE EEEY RQQL SEHS KRGY YGQS ARYR DTEL |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ZO2; X104; FHCA1; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11; TJP2 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasmic side, Nucleus, Peripheral membrane protein, adherens junction, tight junction. |
Calculated MW: | 134kDa |
Observed MW: | 160kDa |
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9414 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |