The TIP49A Rabbit Monoclonal Antibody (CAB5180) is a cutting-edge tool for researchers studying TIP49A, a key player in gene regulation and chromatin remodeling. This antibody, generated using rabbit monoclonal technology, exhibits high specificity and sensitivity in detecting TIP49A in various experimental settings. Validated for use in immunofluorescence and flow cytometry applications, it allows for precise visualization and quantification of TIP49A expression in different cell types.TIP49A, also known as RUVBL1, is a crucial component of chromatin remodeling complexes and is involved in diverse cellular processes such as transcriptional regulation, DNA repair, and cell cycle progression.
Its dysregulation has been implicated in various diseases, including cancer and neurological disorders, making it a promising therapeutic target. By targeting TIP49A, researchers can gain insights into its function and potentially develop novel treatment strategies for associated conditions.
Product Name:
RUVBL1/TIP49A/PONTIN Rabbit Monoclonal Antibody
SKU:
CAB5180
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-456 of human RUVBL1/TIP49A/PONTIN (Q9Y265).
This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8607
Clone Number:
ARC1247
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using RUVBL1/TIP49A/PONTIN Rabbit mAb (CAB5180) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
