The TIMP4 Polyclonal Antibody (CAB6416) is a valuable tool for researchers studying tissue inhibitor of metalloproteinase 4 (TIMP4), a protein involved in the regulation of matrix metalloproteinases and tissue remodeling. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting TIMP4 in human samples, making it ideal for use in applications such as Western blotting.TIMP4 is known to play a crucial role in various physiological processes, including tissue development, wound healing, and cardiovascular health. Dysregulation of TIMP4 expression has been linked to diseases such as cancer, cardiovascular disorders, and fibrosis.
By targeting TIMP4 with this polyclonal antibody, researchers can gain insights into its role in these pathologies and potentially identify new therapeutic targets for intervention.With its ability to specifically bind to TIMP4, this polyclonal antibody opens up opportunities for further investigations into the mechanisms underlying TIMP4 function and its potential as a therapeutic target. Researchers in the fields of molecular biology, cell biology, and biomedicine will find this antibody to be a valuable tool in their quest to unravel the complexities of TIMP4 signaling pathways and their implications in disease progression.
Product Name:
TIMP4 Rabbit Polyclonal Antibody
SKU:
CAB6416
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-224 of human TIMP4 (NP_003247.1).
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Purification Method:
Affinity purification
Gene ID:
7079
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TIMP4 Rabbit pAb (CAB6416) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
