TIMP3 Rabbit Polyclonal Antibody (CAB11986)
- SKU:
- CAB11986
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | TIMP3 Rabbit Polyclonal Antibody |
SKU: | CAB11986 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 110-210 of human TIMP3 (NP_000353.1). |
Sequence: | DGKM YTGL CNFV ERWD QLTL SQRK GLNY RYHL GCNC KIKS CYYL PCFV TSKN ECLW TDML SNFG YPGY QSKH YACI RQKG GYCS WYRG WAPP DKSI INAT D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SFD; K222; K222TA2; HSMRK222; TIMP3 |
Positive Sample: | Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 24kDa |
Observed MW: | 20kDa/25kDa |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Purification Method: | Affinity purification |
Gene ID: | 7078 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |