TIMM8A Rabbit Polyclonal Antibody (CAB9811)
- SKU:
- CAB9811
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TIMM8A Rabbit Polyclonal Antibody |
SKU: | CAB9811 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human TIMM8A (NP_004076.1). |
Sequence: | MDSS SSSS AAGL GAVD PQLQ HFIE VETQ KQRF QQLV HQMT ELCW EKCM DKPG PKLD SRAE ACFV NCVE RFID TSQF ILNR LEQT QKSK PVFS ESLS D |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | DDP; MTS; DDP1; DFN1; TIM8; TIMM8A |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 11kDa |
Observed MW: | 11kDa |
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1678 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |