The TIMM23 Polyclonal Antibody (CAB8688) is a valuable tool for researchers studying the TIMM23 protein, a key component of the mitochondrial import machinery. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to TIMM23, this antibody enables accurate detection and analysis of the protein in a variety of cell types.TIMM23 is essential for the import of nuclear-encoded proteins into the mitochondria, playing a crucial role in maintaining mitochondrial function and cellular metabolism. Dysfunction in TIMM23 has been linked to various diseases, including metabolic disorders and neurodegenerative conditions.
Research on TIMM23 can provide insights into the mechanisms underlying these diseases and may lead to the development of targeted therapies.By utilizing the TIMM23 Polyclonal Antibody, researchers can study the expression and localization of TIMM23 in different cellular contexts, advancing our understanding of mitochondrial protein import and its implications for human health. This antibody is a valuable tool for researchers in the fields of cell biology, metabolism, and mitochondrial biology.
Product Name:
TIMM23 Rabbit Polyclonal Antibody
SKU:
CAB8688
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 7-72 of human TIMM23 (NP_006318.1).
The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
100287932
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TIMM23 antibody (CAB8688) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
