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TIMM22 Monoclonal Antibody

SKU:
CAB23557
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

TIMM22 Monoclonal Antibody (CAB23557)

The TIMM22 Monoclonal Antibody is a valuable tool for researchers studying mitochondrial import inner membrane translocase subunit Tim22 (TIMM22), a crucial component in the import of proteins into the mitochondria. This antibody, produced using hybridoma technology, demonstrates high specificity and sensitivity for detecting TIMM22 in various cell types and tissues, making it ideal for studies in mitochondrial biology and cellular metabolism.TIMM22 plays a pivotal role in the transport of proteins across the inner mitochondrial membrane, contributing to the maintenance of mitochondrial function and cellular homeostasis.

Dysfunction in TIMM22 has been linked to mitochondrial diseases and metabolic disorders, highlighting its importance in cellular health. By utilizing the TIMM22 Monoclonal Antibody, researchers can investigate the role of TIMM22 in mitochondrial protein import and its implications for mitochondrial function and cellular physiology.

Product Name:TIMM22 Monoclonal Antibody
Product Code:CAB23557
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC3118
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Hep G2, Mouse ovary, Rat heart

Multipass transmembrane proteins are brought into mitochondria and inserted into the mitochondrial inner membrane by way of the TIM22 complex. This complex has six subunits and is a twin-pore translocase. The protein encoded by this gene is a subunit of TIM22 and represents the voltage-activated and signal-gated channel.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 20-120aa of human TIMM22.
Sequence:Email for sequence
Synonyms:TEX4, TIM22, COXPD43
Calculated MW:20kDa
Observed MW:20kDa

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