The TIMM17A Polyclonal Antibody (CAB6449) is a valuable tool for research involving TIMM17A, a key protein involved in mitochondrial protein import and assembly. This antibody, produced in rabbits, is highly specific to TIMM17A and has been validated for use in various applications such as Western blot and immunofluorescence.TIMM17A is an essential component of the mitochondrial inner membrane translocase complex, which plays a crucial role in the import of nuclear-encoded proteins into the mitochondria. Dysfunction of TIMM17A has been associated with various mitochondrial disorders and diseases, making it a promising target for research into mitochondrial function and related pathologies.
By using the TIMM17A Polyclonal Antibody, researchers can effectively detect and analyze TIMM17A levels and localization in different cell types, providing valuable insights into mitochondrial protein import mechanisms. This antibody is a valuable tool for studies in cell biology, biochemistry, and mitochondrial research, enabling a better understanding of the role of TIMM17A in cellular function and disease.
Product Name:
TIMM17A Rabbit Polyclonal Antibody
SKU:
CAB6449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human TIMM17A (NP_006326.1).
Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial inner membrane and nucleoplasm. Is integral component of mitochondrial inner membrane. Part of TIM23 mitochondrial import inner membrane translocase complex.
Purification Method:
Affinity purification
Gene ID:
10440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TIMM17A antibody (CAB6449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
