The TIMM10 Polyclonal Antibody (CAB4626) is a valuable tool for researchers investigating TIMM10, a protein involved in mitochondrial import. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the TIMM10 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component of studies in mitochondrial biology and bioenergetics.TIMM10 is a critical component of the mitochondrial protein import machinery, facilitating the translocation of nuclear-encoded proteins into the mitochondria.
Dysregulation of TIMM10 has been implicated in various mitochondrial disorders and neurodegenerative diseases, highlighting its importance in maintaining mitochondrial function and cellular homeostasis. Research on TIMM10 is essential for understanding the mechanisms underlying these disorders and developing targeted therapies to treat them.Overall, the TIMM10 Polyclonal Antibody serves as a valuable tool for investigating the role of TIMM10 in mitochondrial biology and disease pathogenesis, providing researchers with the means to further elucidate its functions and potential therapeutic applications.
Product Name:
TIMM10 Rabbit Polyclonal Antibody
SKU:
CAB4626
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human TIMM10 (NP_036588.1).
The mitochondrial protein encoded by this gene belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane, functioning as intermembrane space chaperones for the highly insoluble carrier proteins.
Purification Method:
Affinity purification
Gene ID:
26519
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TIMM10 Rabbit pAb (CAB4626) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
