TIMELESS Rabbit Polyclonal Antibody (CAB4261)
- SKU:
- CAB4261
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TIMELESS Rabbit Polyclonal Antibody |
SKU: | CAB4261 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 969-1208 of human TIMELESS (NP_003911.2). |
Sequence: | EDLE EEEN LPEE DSEE EEEG GSEA EQVQ GSLV LSNE NLGQ SLHQ EGFS IPLL WLQN CLIR AADD REED GCSQ AVPL VPLT EENE EAME NEQF QQLL RKLG VRPP ASGQ ETFW RIPA KLSP TQLR RAAA SLSQ PEEE QKLQ PELQ PKVP GEQG SDEE HCKE HRAQ ALRA LLLA HKKK AGLA SPEE EDAV GKEP LKAA PKKR QLLD SDEE QEED EGRN RAPE LGAP GIQK KKRY QIED DEDD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TIM; TIM1; hTIM; FASPS4; TIMELESS |
Positive Sample: | BxPC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 139kDa |
Observed MW: | 160kDa |
The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.
Purification Method: | Affinity purification |
Gene ID: | 8914 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |