TICAM1 Rabbit Polyclonal Antibody (CAB13605)
- SKU:
- CAB13605
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TICAM1 Rabbit Polyclonal Antibody |
SKU: | CAB13605 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human TRIF/TICAM1 (NP_891549.1). |
Sequence: | QDKL LYLK HKLK TPRP GCQG QDLL HAMV LLKL GQET EARI SLEA LKAD AVAR LVAR QWAG VDST EDPE EPPD VSWA VARL YHLL AEEK LCPA SLRD VAYQ EAVR TLSS RDDH RLGE LQDE ARNR CGWD IAGD PGSI RTLQ SNLG CLPP SSAL PSGT RSLP RPID GVSD WSQG CSLR STGS P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF/TICAM1 |
Positive Sample: | Raji,Mouse spleen,Mouse eye,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic vesicle, autophagosome. |
Calculated MW: | 76kDa |
Observed MW: | 70kDa |
This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. Mutations in this gene are associated with encephalopathy, acute, infection-induced.
Purification Method: | Affinity purification |
Gene ID: | 148022 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |