The Thymidine Kinase 1 Rabbit Monoclonal Antibody is specifically designed for research involving the Thymidine Kinase 1 protein, an enzyme involved in DNA synthesis and cell proliferation. This antibody is raised in rabbits and is highly reactive with human samples, making it a valuable tool for studying the role of Thymidine Kinase 1 in various biological processes.Thymidine Kinase 1 is known to be overexpressed in rapidly dividing cells, such as cancer cells, making it a potential target for cancer therapy and diagnosis. By detecting and analyzing the Thymidine Kinase 1 protein in different cell types, researchers can gain insights into its function and potential therapeutic implications.
This antibody is validated for use in Western blot applications, allowing for accurate and reliable detection of Thymidine Kinase 1 in experimental settings. Its high specificity and sensitivity make it an ideal choice for studies in cancer research, cell biology, and molecular biology.Overall, the Thymidine Kinase 1 Rabbit Monoclonal Antibody offers a valuable tool for researchers looking to investigate the role of Thymidine Kinase 1 in various biological processes, particularly in the context of cancer biology and cell proliferation.
Product Name:
Thymidine Kinase 1 Rabbit Monoclonal Antibody
SKU:
CAB13612
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thymidine Kinase 1 (P04183).
The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.
Purification Method:
Affinity purification
Gene ID:
7083
Clone Number:
ARC0719
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Thymidine Kinase 1 Rabbit mAb (CAB13612) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
