The THUMPD3 Polyclonal Antibody (CAB10407) is a vital tool for research involving the THUMP domain-containing protein 3 (THUMPD3), a protein involved in RNA modification processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the THUMPD3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and RNA modification research.THUMPD3 is an essential player in the RNA modification pathway, specifically in the formation of 2'-O-methylated pseudouridines in tRNA molecules.
Understanding the function and regulation of THUMPD3 is crucial for deciphering the intricate mechanisms of RNA modification and its impact on cellular processes. Research on THUMPD3 could potentially shed light on its involvement in diseases related to RNA dysregulation, such as neurological disorders and cancer. The THUMPD3 Polyclonal Antibody is a valuable tool for scientists aiming to unravel the mysteries of RNA modification and its implications in human health and disease.
Product Name:
THUMPD3 Rabbit Polyclonal Antibody
SKU:
CAB10407
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human THUMPD3 (NP_056268.2).
Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Located in cytosol and nucleolus.
Purification Method:
Affinity purification
Gene ID:
25917
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using THUMPD3 Rabbit pAb (CAB10407) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
