The THTPA Polyclonal Antibody (PAC041830) is a valuable tool for researchers studying THTPA, an enzyme involved in thiamine metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in immunohistochemistry applications. By specifically recognizing the THTPA protein, researchers can accurately detect and study THTPA expression in various tissues and cell types.THTPA plays a crucial role in thiamine metabolism, which is essential for the proper functioning of cells and energy production. Dysregulation of THTPA has been linked to thiamine deficiency disorders and other metabolic conditions.
By studying the expression and activity of THTPA, researchers can gain insights into thiamine-related diseases and potential therapeutic targets.With its versatile applications in immunohistochemistry, the THTPA Polyclonal Antibody is an invaluable tool for researchers investigating thiamine metabolism, metabolic disorders, and cellular energy production. Its high specificity and sensitivity make it a reliable choice for research in biochemistry, metabolism, and related fields.
Antibody Name:
THTPA Antibody (PACO41830)
Antibody SKU:
PACO41830
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Thiamine-triphosphatase protein (2-230AA)
THTP: Hydrolase highly specific for thiamine triphosphate (ThTP). Belongs to the ThTPase family.Protein type: Cofactor and Vitamin Metabolism - thiamine; EC 3.6.1.28; HydrolaseChromosomal Location of Human Ortholog: 14q11.2Cellular Component: cytosolMolecular Function: hydrolase activity; magnesium ion binding; thiamin-triphosphatase activityBiological Process: dephosphorylation; thiamin and derivative metabolic process; thiamin diphosphate metabolic process; thiamin metabolic process
UniProt Protein Details:
NCBI Summary:
This gene encodes an enzyme which catalyzes the biosynthesis of thiamine disphophate (vitamin B1) by hydrolysis of thiamine triphosphate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
