The THRSP Polyclonal Antibody (PAC046610) is a valuable tool for researching THRSP, a protein involved in lipid metabolism and energy homeostasis. This antibody, raised in rabbits, has high specificity for human samples and is validated for Western blot applications. By binding to the THRSP protein, researchers can accurately detect and analyze THRSP levels in various cell types, making it ideal for studies in metabolic disorders, obesity, and related diseases.THRSP, also known as thyroid hormone-responsive protein, plays a critical role in regulating lipid synthesis and storage in the body.
Its involvement in maintaining energy balance and lipid metabolism makes it a promising target for investigating metabolic diseases and conditions linked to dysregulated lipid metabolism. Understanding the function of THRSP is essential for developing potential therapies that target lipid metabolism and energy regulation in metabolic disorders.
Antibody Name:
Thrsp Antibody (PACO46610)
Antibody SKU:
PACO46610
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Thyroid hormone-inducible hepatic protein (1-150AA)
Immunofluorescent analysis of MCF-7 cells using PACO46610 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid, chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB (By similarity).
THRSP: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. Belongs to the SPOT14 family.Protein type: Unknown functionCellular Component: nucleoplasm; cytoplasm; nucleus; cytosolMolecular Function: protein binding; protein homodimerization activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; lipid metabolic process; regulation of lipid biosynthetic process
