Thromboxane synthase Rabbit Monoclonal Antibody (CAB5173)
- SKU:
- CAB5173
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
Product Name: | Thromboxane synthase Rabbit Monoclonal Antibody |
SKU: | CAB5173 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thromboxane synthase (P24557). |
Sequence: | MEAL GFLK LEVN GPMV TVAL SVAL LALL KWYS TSAF SRLE KLGL RHPK PSPF IGNL TFFR QGFW ESQM ELRK LYGP LCGY YLGR RMFI VISE PDMI KQVL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14; Thromboxane synthase |
Positive Sample: | A549,Mouse lung,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 61kDa |
Observed MW: | 60kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6916 |
Clone Number: | ARC1189 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |