The Thromboxane Synthase Rabbit Monoclonal Antibody (CAB5173) is a key tool for researchers studying thromboxane synthase, an enzyme involved in the production of thromboxane, a potent vasoconstrictor and platelet aggregator. This antibody, developed in rabbits, exhibits high specificity and sensitivity for detecting thromboxane synthase in various samples, making it suitable for use in Western blot and immunohistochemistry applications.Thromboxane synthase plays a crucial role in the regulation of vascular tone, platelet aggregation, and inflammation, making it a promising target for understanding cardiovascular diseases, thrombotic disorders, and inflammatory conditions.
By utilizing this monoclonal antibody, researchers can accurately detect and quantify thromboxane synthase levels in different tissues and cell types, facilitating detailed investigations into its biological functions and potential therapeutic applications.Overall, the Thromboxane Synthase Rabbit Monoclonal Antibody (CAB5173) provides researchers with a reliable tool for advancing their studies on thromboxane synthase and its implications in various disease processes, offering valuable insights for drug discovery and development in the field of cardiovascular and inflammatory research.
Product Name:
Thromboxane synthase Rabbit Monoclonal Antibody
SKU:
CAB5173
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thromboxane synthase (P24557).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6916
Clone Number:
ARC1189
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Thromboxane synthase Rabbit mAb (CAB5173) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
