The Thrombospondin-3 Polyclonal Antibody (CAB3641) is a vital tool for researchers studying Thrombospondin-3 (THBS3), a glycoprotein that plays a crucial role in cell adhesion, migration, and tissue remodeling. This antibody, generated in rabbits, exhibits high reactivity with human THBS3 samples and has been validated for use in Western blot applications. By targeting the THBS3 protein, this antibody enables the precise detection and analysis of THBS3 expression in various cell types, making it an indispensable tool for investigations in the fields of cell biology, tissue engineering, and cancer research.THBS3 is a multifunctional protein involved in various physiological processes, including angiogenesis, wound healing, and fibrosis.
Its dysregulation has been linked to several pathological conditions, such as cancer progression, fibrotic diseases, and cardiovascular disorders. Given its diverse roles in cellular processes, understanding the mechanisms of THBS3 function is crucial for developing targeted therapies and diagnostic tools for these diseases. The Thrombospondin-3 Polyclonal Antibody (CAB3641) provides researchers with a reliable means to investigate the role of THBS3 in health and disease, paving the way for advancements in medical research and therapeutic interventions.
Product Name:
THBS3 Rabbit Polyclonal Antibody
SKU:
CAB3641
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 787-956 of human THBS3 (NP_009043.1).
extracellular region, perinuclear region of cytoplasm
Calculated MW:
104kDa
Observed MW:
104kDa
The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants.
Purification Method:
Affinity purification
Gene ID:
7059
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using THBS3 antibody (CAB3641) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
