The Thrombospondin-1 Polyclonal Antibody (CAB2125) is a valuable tool for researchers studying Thrombospondin-1, a glycoprotein involved in cell adhesion, migration, and tissue repair. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot and immunohistochemistry applications. By binding to Thrombospondin-1, researchers can detect and analyze this important protein in a variety of cell types, making it a versatile tool for studies in cardiovascular disease, cancer, and wound healing.Thrombospondin-1 is known to play a critical role in angiogenesis, inflammation, and tissue remodeling, making it a key target for research into diseases such as atherosclerosis, arthritis, and cancer.
By understanding the function of Thrombospondin-1 and its interactions with other molecules, researchers can develop new therapeutic strategies aimed at modulating its activity for the treatment of various pathological conditions. The Thrombospondin-1 Polyclonal Antibody is essential for elucidating the role of this glycoprotein in health and disease, providing valuable insights for drug development and personalized medicine.
Product Name:
THBS1 Rabbit Polyclonal Antibody
SKU:
CAB2125
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-352 of human THBS1 (NP_003237.2).
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
Purification Method:
Affinity purification
Gene ID:
7057
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251 MG cells using THBS1 Rabbit pAb(CAB2125) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
