THPO Rabbit Polyclonal Antibody (CAB1825)
- SKU:
- CAB1825
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | THPO Rabbit Polyclonal Antibody |
SKU: | CAB1825 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-349 of human THPO (NP_001171068.1). |
Sequence: | SPAP PACD LRVL SKLL RDSH VLHS RLSQ CPEV HPLP TPVL LPAV DFSL GEWK TQME ETKA QDIL GAVT LLLE GVMA ARGQ LGPT CLSS LLGQ LSGQ VRLL LGAL QSLL GTQG RTTA HKDP NAIF LSFQ HLLR GKVR FLML VGGS TLCV RRAP PTTA VPSR TSLV LTLN ELPN RTSG LLET NFTA SART TGSG LLKW QQGF RAKI PGLL NQTS RSLD QIPG YLNR IHEL LNGT RGLF PGPS RRTL GAPD ISSG TSDT GSLP PNLQ PGYS PSPT HPPT GQYT LFPL PPTL PTPV VQLH PLLP DPSA PTPT PTSP LLNT SYTH SQNL SQEG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ML; TPO; MGDF; MKCSF; MPLLG; THCYT1; THPO |
Positive Sample: | SH-SY5Y,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
Purification Method: | Affinity purification |
Gene ID: | 7066 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |