THBD Rabbit Polyclonal Antibody (CAB4155)
- SKU:
- CAB4155
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | THBD Rabbit Polyclonal Antibody |
SKU: | CAB4155 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-515 of human CD141/Thrombomodulin (NP_000352.1). |
Sequence: | APAE PQPG GSQC VEHD CFAL YPGP ATFL NASQ ICDG LRGH LMTV RSSV AADV ISLL LNGD GGVG RRRL WIGL QLPP GCGD PKRL GPLR GFQW VTGD NNTS YSRW ARLD LNGA PLCG PLCV AVSA AEAT VPSE PIWE EQQC EVKA DGFL CEFH FPAT CRPL AVEP GAAA AAVS ITYG TPFA ARGA DFQA LPVG SSAA VAPL GLQL MCTA PPGA VQGH WARE APGA WDCS VENG GCEH ACNA IPGA PRCQ CPAG AALQ ADGR SCTA SATQ SCND LCEH FCVP NPDQ PGSY SCMC ETGY RLAA DQHR CEDV DDCI LEPS PCPQ RCVN TQGG FECH CYPN YDLV DGEC VEPV DPCF RANC EYQC QPLN QTSY LCVC AEGF APIP HEPH RCQM FCNQ TACP ADCD PNTQ ASCE CPEG YILD DGFI CTDI DECE NGGF CSGV CHNL PGTF ECIC GPDS ALAR HIGT DCDS GKVD GGDS GSGE PPPS PTPG STLT PPAV GLVH S |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12; CD141/Thrombomodulin |
Positive Sample: | A-431,A-549,THP-1,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | 110kDa |
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Purification Method: | Affinity purification |
Gene ID: | 7056 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |