The Thrombin-like Enzyme Crotalase Antibody (PACO35090) is a crucial tool for researchers studying snake venom toxins, specifically those with thrombin-like activity. This polyclonal antibody, raised in rabbits, demonstrates high reactivity with crotalase and related enzymes, making it ideal for use in assays and experiments focused on understanding the mechanisms of snake venom-induced coagulopathy.Crotalase, a snake venom enzyme from Crotalus adamanteus (Eastern Diamondback Rattlesnake), has been shown to cleave fibrinogen and fibrin, leading to blood clotting disorders. The PACO35090 antibody binds specifically to crotalase, enabling researchers to detect and quantify its presence in samples from various experimental models.
Given the role of thrombin-like enzymes in snake venom toxicity and their potential implications for antivenom development, the Thrombin-like Enzyme Crotalase Antibody is a valuable tool for investigators in the fields of toxinology, hematology, and pharmacology. By utilizing this antibody in their research, scientists can gain valuable insights into the pathophysiology of snakebite envenomation and potentially contribute to the development of more effective treatments for snakebite victims.
