The THOC7 Polyclonal Antibody (CAB13700) is a valuable tool for researchers studying THOC7, a crucial component of the TREX (Transcription/export) complex which plays a key role in mRNA export from the nucleus to the cytoplasm. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.THOC7 is essential for mRNA export and its dysregulation has been linked to various diseases including cancer and neurodegenerative disorders.
By targeting THOC7, researchers can investigate its role in mRNA transport and its impact on gene expression, making this antibody ideal for studies in molecular biology, genetics, and oncology research.Overall, the THOC7 Polyclonal Antibody provides a reliable tool for probing the function of THOC7 in cellular processes and disease pathways, offering new insights into RNA transport mechanisms and potential therapeutic targets.
Product Name:
THOC7 Rabbit Polyclonal Antibody
SKU:
CAB13700
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human THOC7 (NP_079351.2).
Predicted to enable RNA binding activity. Involved in mRNA export from nucleus and viral mRNA export from host cell nucleus. Located in cytosol and nuclear speck. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region.
Purification Method:
Affinity purification
Gene ID:
80145
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using THOC7 Rabbit pAb (CAB13700) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
