The THOC5 Polyclonal Antibody (CAB11635) is a vital tool for researchers studying THOC5, a protein involved in mRNA processing and transport. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the THOC5 protein, this antibody enables the detection and analysis of THOC5 in a variety of cell types, making it ideal for investigations in molecular biology and gene expression research.
THOC5 is a key player in cellular processes related to gene expression, including mRNA export from the nucleus to the cytoplasm. Dysfunction of THOC5 has been linked to various diseases, such as cancer and neurological disorders, highlighting its importance in biological pathways. Research on THOC5 can provide valuable insights into the mechanisms underlying these conditions and pave the way for potential therapeutic interventions targeting THOC5-related pathways.
Product Name:
THOC5 Rabbit Polyclonal Antibody
SKU:
CAB11635
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-370 of human THOC5 (NP_003669.4).
Predicted to enable mRNA binding activity. Involved in several processes, including monocyte differentiation; negative regulation of DNA damage checkpoint; and viral mRNA export from host cell nucleus. Located in nucleoplasm. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. Implicated in breast carcinoma.
Purification Method:
Affinity purification
Gene ID:
8563
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using THOC5 Rabbit pAb (CAB11635) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
