The THOC2 Polyclonal Antibody (CAB18332) is a valuable tool for researchers studying THOC2, a protein involved in mRNA export from the nucleus to the cytoplasm. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the THOC2 protein, this antibody allows for the detection and analysis of THOC2 in various cell types, making it ideal for studies in molecular biology and gene expression.THOC2 plays a crucial role in the regulation of gene expression by facilitating the transport of mRNA molecules, ensuring proper protein synthesis.
Dysregulation of THOC2 function has been associated with various diseases, including cancer and neurological disorders. Therefore, understanding the role of THOC2 in mRNA export is essential for identifying potential therapeutic targets and developing treatments for these conditions.Overall, the THOC2 Polyclonal Antibody (CAB18332) is a reliable tool for researchers interested in investigating the molecular mechanisms underlying mRNA export and its implications in human health and disease.
Product Name:
THOC2 Rabbit Polyclonal Antibody
SKU:
CAB18332
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human THOC2 (NP_001075019.1).
The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded protein interacts with the THOC1 protein.
Purification Method:
Affinity purification
Gene ID:
57187
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using THOC2 Rabbit pAb (CAB18332) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
