Nuclear Matrix Protein p84 (THOC1) Rabbit Polyclonal Antibody (CAB8179)
The THOC1 Polyclonal Antibody (CAB8179) is a valuable tool for researchers studying THOC1, a protein involved in mRNA processing and export. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the THOC1 protein, this antibody enables researchers to detect and analyze THOC1 expression in various cell types, making it an ideal choice for studies in molecular biology and gene expression regulation.THOC1 plays a crucial role in the transportation of mRNA from the nucleus to the cytoplasm, ensuring the proper functioning of gene expression processes.
Dysregulation of THOC1 has been linked to various diseases, including cancer, developmental disorders, and neurological conditions. Understanding the function and regulation of THOC1 is vital for unraveling the molecular mechanisms underlying these diseases and may lead to the development of therapeutic interventions targeting mRNA processing pathways.
Product Name:
Nuclear Matrix Protein p84 (THOC1) Rabbit Polyclonal Antibody
SKU:
CAB8179
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 428-657 of human Nuclear Matrix Protein p84 (Nuclear Matrix Protein p84 (THOC1)) (NP_005122.2).
Predicted to enable DNA binding activity and RNA binding activity. Involved in several processes, including negative regulation of DNA damage checkpoint; regulation of nucleobase-containing compound metabolic process; and viral mRNA export from host cell nucleus. Located in cytoplasm and nuclear speck. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region.
Purification Method:
Affinity purification
Gene ID:
9984
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Nuclear Matrix Protein p84 (THOC1) Rabbit pAb (CAB8179) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
