The Thio Polyclonal Antibody (PACO35098) is a valuable tool for researchers studying thio-containing molecules in biological systems. This antibody, generated in rabbits, demonstrates high reactivity towards thio-containing proteins, enabling detection and analysis in a variety of samples. Validated for use in Western blot applications, the Thio antibody allows for precise identification of thio-modified proteins in cell lysates or tissue samples.Thio-containing molecules play a vital role in various cellular processes, including protein folding, enzyme catalysis, and redox signaling. The Thio Polyclonal Antibody provides researchers with a reliable method to study the functions and regulation of thio-modified proteins, making it an essential tool for investigations in biochemistry, molecular biology, and drug discovery.
By targeting thio-containing proteins, researchers can delve deeper into understanding the mechanisms underlying diseases like cancer, neurodegenerative disorders, and metabolic diseases. The Thio Polyclonal Antibody offers a versatile and powerful tool for elucidating the roles of thio-modifications in health and disease, paving the way for the development of novel therapeutic strategies targeting thio-containing molecules.
Antibody Name:
thiO Antibody (PACO35098)
Antibody SKU:
PACO35098
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Bacillus subtilis
Immunogen:
Recombinant Bacillus subtilis Glycine oxidase protein (1-369AA)
Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acid, to yield the corresponding alpha-keto acid, , ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine), N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine, D-valine, D-proline and D-methionine. Does not act on L-amino acid, and other D-amino acid,. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate.
Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha-keto acids, ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine), N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine, D-valine, D-proline and D-methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate.
