Similarly, the Thiaminase-1 Polyclonal Antibody (PACO53790) offered by Assay Genie is a powerful tool for researchers studying thiaminase-1, an enzyme involved in thiamine (vitamin B1) metabolism. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications, enabling the detection and analysis of thiaminase-1 in various biological samples.Thiaminase-1 plays a crucial role in thiamine catabolism, which is essential for energy metabolism and proper functioning of the nervous system. Dysregulation of thiamine metabolism, including thiaminase-1 activity, has been linked to various conditions such as beriberi and Wernicke-Korsakoff syndrome.
By targeting thiaminase-1, researchers can gain insights into the mechanisms underlying these diseases and potentially develop new therapeutic strategies.With its high specificity and sensitivity, the Thiaminase-1 Polyclonal Antibody is an invaluable tool for investigating the role of thiaminase-1 in health and disease. Whether studying thiamine metabolism, neurological disorders, or other related fields, researchers can rely on this antibody to facilitate their research efforts and advance scientific understanding in these areas.
Antibody Name:
Thiaminase-1 Antibody (PACO53790)
Antibody SKU:
PACO53790
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Paenibacillus thiaminolyticus
Immunogen:
Recombinant Paenibacillus thiaminolyticus Thiaminase-1 protein (30-409AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: Thiaminase-1 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 58 kDa. Observed band size: 58 kDa.
Background:
Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles.
