The THBS4 Polyclonal Antibody (CAB16438) is a valuable tool for researchers studying THBS4, a matricellular protein involved in cell-matrix interactions and tissue remodeling. This antibody, generated in rabbits, is highly specific and sensitive, making it ideal for use in various laboratory techniques such as Western blotting and immunohistochemistry.THBS4, also known as Thrombospondin-4, is known to play a critical role in tumor growth and angiogenesis, making it a promising target for cancer research.
Additionally, THBS4 has been implicated in cardiovascular disease and musculoskeletal disorders, highlighting its importance in multiple areas of biomedical research.By using the THBS4 Polyclonal Antibody, researchers can gain insights into the function and regulation of THBS4 in various biological processes, paving the way for the development of novel therapeutic strategies targeting THBS4-related pathways.
Product Name:
THBS4 Rabbit Polyclonal Antibody
SKU:
CAB16438
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human THBS4 (NP_003239.2).
The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7060
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using THBS4 Rabbit pAb (CAB16438) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 150s.
