The THBS1 Polyclonal Antibody (CAB16985) is a valuable tool for researchers studying THBS1, a protein involved in cell adhesion, migration, and angiogenesis. This rabbit-derived antibody is highly specific to human THBS1 and has been validated for use in Western blot applications. By targeting THBS1, this antibody allows for the detection and analysis of THBS1 expression in various cell types, making it an essential tool for studies in biology and cancer research.THBS1, also known as thrombospondin-1, plays a crucial role in mediating cell-cell and cell-matrix interactions, making it a key player in processes such as wound healing, tissue remodeling, and tumor progression.
Understanding the function of THBS1 is essential for unraveling its contributions to normal physiology and disease development, particularly in the context of cancer, cardiovascular diseases, and neurodegenerative disorders. By investigating the role of THBS1 using this polyclonal antibody, researchers can gain valuable insights that may inform future therapeutic strategies targeting THBS1-related pathways.
Product Name:
THBS1 Rabbit Polyclonal Antibody
SKU:
CAB16985
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human THBS1 (NP_003237.2).
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
Purification Method:
Affinity purification
Gene ID:
7057
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using THBS1 Rabbit pAb (CAB16985) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
