The THAP9 Monoclonal Antibody (PAC020676) is a valuable tool for research involving THAP9, a member of the THAP (Thanatos-associated protein) family known for its involvement in a variety of cellular processes. This antibody, produced using state-of-the-art technology, is highly specific for THAP9 and suitable for a range of applications, including immunofluorescence and immunohistochemistry.THAP9 is a nuclear protein that has been implicated in gene regulation, cell cycle control, and apoptosis.
Its diverse functions make it an intriguing target for further study in the fields of molecular biology and cancer research. With the ability to specifically detect THAP9 in cells and tissues, this antibody provides researchers with a powerful tool for investigating the role of THAP9 in health and disease.
Antibody Name:
THAP9 Antibody (PACO20676)
Antibody SKU:
PACO20676
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human THAP9
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20676(THAP9 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
THAP9 (THAP domain-containing protein 9) is a 903 amino acid, protein that contains one THAP-type zinc finger. The gene that encodes THAP9 contains roughly 19,448 bases and maps to human chromosome 4q21.22. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acid, mia and polycystic kidney disease.
Synonyms:
THAP domain containing 9
UniProt Protein Function:
THAP9: Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transpositionChromosomal Location of Human Ortholog: 4q21.22Molecular Function: transferase activity; sequence-specific DNA binding; metal ion binding; transposase activityBiological Process: DNA integration; transposition, DNA-mediated; DNA recombination
