The TGS1 Polyclonal Antibody (CAB7848) is a vital tool for researchers studying the TGS1 protein, which plays a crucial role in RNA modification and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TGS1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and genetics research.TGS1 is an essential enzyme involved in the methylation of small nuclear RNAs, impacting various cellular processes such as RNA splicing and gene expression.
It is implicated in the maintenance of genome stability and the regulation of RNA metabolism, making it a key target for studies related to RNA modification and cellular function. Understanding the function and regulation of TGS1 can provide valuable insights into mechanisms of gene expression and potential therapeutic targets for diseases related to RNA processing abnormalities.
Product Name:
TGS1 Rabbit Polyclonal Antibody
SKU:
CAB7848
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 714-853 of human TGS1 (NP_079107.6).
Enables RNA trimethylguanosine synthase activity. Involved in 7-methylguanosine cap hypermethylation. Located in cytosol and nucleus.
Purification Method:
Affinity purification
Gene ID:
96764
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TGS1 antibody (CAB7848) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
