The TgolN2 Polyclonal Antibody (CAB16707) is specifically designed for research involving the Golgi-specific protein TgolN2, involved in intracellular transport and protein trafficking. This antibody, produced through rabbit immunization, is highly reactive with human samples and is validated for use in various applications, including immunofluorescence and immunohistochemistry.TgolN2 is a crucial component of the Golgi apparatus, responsible for the modification, sorting, and packaging of proteins for transport to different cellular locations. Its role in intracellular trafficking makes it a key target for studies in cell biology, biochemistry, and neurobiology.
By targeting TgolN2 with this antibody, researchers can visualize and study the distribution and function of this protein within cells, providing valuable insights into cellular processes and mechanisms.Furthermore, understanding the function of TgolN2 is essential for unraveling its involvement in various cellular processes and diseases, including neurodegenerative disorders, metabolic syndromes, and cancer. The TgolN2 Polyclonal Antibody offers a reliable tool for investigating the role of TgolN2 in these contexts, contributing to advancements in biomedical research and potential therapeutic development.
Product Name:
TGN46/TGOLN2 Rabbit Polyclonal Antibody
SKU:
CAB16707
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 323-423 of human TGN46/TGN46/TGOLN2 (NP_006455.2).
Cell membrane, Golgi apparatus, Single-pass type I membrane protein, trans-Golgi network membrane.
Calculated MW:
46kDa
Observed MW:
110kDa
This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TGN46/TGOLN2 Rabbit pAb (CAB16707) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
