TGFBR3 Rabbit Polyclonal Antibody (CAB0627)
- SKU:
- CAB0627
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TGFBR3 Rabbit Polyclonal Antibody |
SKU: | CAB0627 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-340 of human TGFBR3 (NP_003234.2). |
Sequence: | ANFS LTAE TEER NFPH GNEH LLNW ARKE YGAV TSFT ELKI ARNI YIKV GEDQ VFPP KCNI GKNF LSLN YLAE YLQP KAAE GCVM SSQP QNEE VHII ELIT PNSN PYSA FQVD ITID IRPS QEDL EVVK NLIL ILKC KKSV NWVI KSFD VKGS LKII APNS IGFG KESE RSMT MTKS IRDD IPST QGNL VKWA LDNG YSPI T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | BGCAN; betaglycan; TGFBR3 |
Positive Sample: | SH-SY5Y,Mouse brain,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space. |
Calculated MW: | 93kDa |
Observed MW: | 110kDa |
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7049 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |