TGF beta Receptor I (TGFBR1) Rabbit Polyclonal Antibody (CAB16983)
The TGFBR1 Polyclonal Antibody (CAB16983) is a powerful tool for researchers studying the TGFBR1 protein, a key receptor involved in the TGF-beta signaling pathway. This custom antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.TGFBR1, also known as Transforming Growth Factor Beta Receptor 1, plays a crucial role in cellular processes such as cell growth, differentiation, and apoptosis. Dysregulation of TGFBR1 signaling has been implicated in various diseases, including cancer, fibrosis, and immune disorders.
By targeting TGFBR1 with this antibody, researchers can investigate the role of this receptor in different cell types and experimental conditions.With its high specificity and reliability, the TGFBR1 Polyclonal Antibody is an essential tool for scientists conducting research in the fields of cell biology, immunology, and cancer research. By enabling the detection and analysis of TGFBR1 protein levels, this antibody contributes to a better understanding of the TGF-beta signaling pathway and its implications in human health and disease.
Product Name:
TGF beta Receptor I (TGFBR1) Rabbit Polyclonal Antibody
SKU:
CAB16983
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 161-179 of human TGF beta Receptor I (TGFBR1) (NP_004603.1).
Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction.
Calculated MW:
56kDa
Observed MW:
56kDa
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7046
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using TGF beta Receptor I (TGFBR1) Rabbit pAb (CAB16983) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
