TGF beta Receptor I (TGFBR1) Rabbit Polyclonal Antibody (CAB16983)
- SKU:
- CAB16983
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | TGF beta Receptor I (TGFBR1) Rabbit Polyclonal Antibody |
SKU: | CAB16983 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 161-179 of human TGF beta Receptor I (TGFBR1) (NP_004603.1). |
Sequence: | EEDP SLDR PFIS EGTT LKD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I; TGF beta Receptor I (TGFBR1) |
Positive Sample: | PC-3,Mouse lung |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7046 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |