The TGFBI Rabbit Monoclonal Antibody (CAB2407) is a cutting-edge tool for researchers investigating Transforming Growth Factor Beta-Induced (TGFBI) protein, a key player in cellular processes such as cell adhesion, migration, and proliferation. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity in detecting TGFBI in human samples, making it a reliable choice for Western blot experiments.TGFBI, also known as BIGH3, has been implicated in various diseases, including corneal dystrophies, cancer metastasis, and fibrotic disorders. By targeting TGFBI with this antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.
The versatility of this antibody allows for its use in a wide range of cell types and experimental setups, making it an essential tool for studies in cell biology, oncology, and tissue engineering.Overall, the TGFBI Rabbit Monoclonal Antibody (CAB2407) offers researchers a reliable and sensitive tool for investigating the role of TGFBI in cellular processes and disease pathogenesis, paving the way for new advancements in biomedical research.
Product Name:
TGF beta induced TGFBI Rabbit Monoclonal Antibody
SKU:
CAB2407
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TGF beta induced (TGFBI) (Q15582).
Secreted, extracellular matrix, extracellular space
Calculated MW:
75kDa
Observed MW:
66kDa
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
Purification Method:
Affinity purification
Gene ID:
7045
Clone Number:
ARC0757
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using TGF beta induced TGF beta induced (TGFBI) Rabbit mAb (CAB2407) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
