The TGFBI Polyclonal Antibody (CAB2561) is a valuable tool for researchers studying TGFBI (Transforming Growth Factor Beta-Induced), a protein involved in cell adhesion and migration, as well as various biological processes such as cell proliferation and differentiation. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.TGFBI is known for its role in tumorigenesis and metastasis in various cancer types, making it a promising target for cancer research.
By binding specifically to TGFBI protein, this antibody enables detection and analysis of TGFBI in a variety of cell types, making it ideal for studies in oncology and cell biology.Understanding the function and regulation of TGFBI is crucial for developing targeted therapies for cancer and other diseases where TGFBI plays a role. This polyclonal antibody provides researchers with a reliable tool to study TGFBI and its potential as a therapeutic target.
Product Name:
TGF beta induced TGFBI Rabbit Polyclonal Antibody
SKU:
CAB2561
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_000349.1).
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
Purification Method:
Affinity purification
Gene ID:
7045
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TGF beta induced (TGFBI) Rabbit pAb (CAB2561) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
