The TGFBI Polyclonal Antibody (CAB11222) is a valuable tool for researchers studying Transforming Growth Factor Beta-Induced (TGFBI), a protein known to regulate cell adhesion, migration, and proliferation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for TGFBI in human samples, making it ideal for Western blot applications.TGFBI is involved in various cellular processes, including wound healing, angiogenesis, and fibrosis, and dysregulation of TGFBI has been linked to conditions such as cancer and corneal dystrophies.
By targeting TGFBI with this antibody, researchers can gain insights into its role in disease pathology and potential therapeutic strategies.With its ability to detect and analyze TGFBI expression in a wide range of cell types, the TGFBI Polyclonal Antibody (CAB11222) is a valuable tool for studies in cell biology, oncology, and tissue remodeling. By understanding the function of TGFBI, researchers can uncover new opportunities for developing targeted treatments and improving patient outcomes.
Product Name:
TGF beta induced TGFBI Rabbit Polyclonal Antibody
SKU:
CAB11222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_000349.1).
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
Purification Method:
Affinity purification
Gene ID:
7045
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TGF beta induced (TGFBI) antibody (CAB11222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
