The TGFB1 Polyclonal Antibody (CAB8459) is a valuable tool for researchers studying TGFB1, a key signaling protein involved in a wide range of biological processes, including cell growth, differentiation, and immune response regulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications.TGFB1, also known as transforming growth factor beta 1, is a potent regulator of cell growth and differentiation, playing a critical role in tissue development and repair. Dysregulation of TGFB1 signaling has been implicated in various diseases, including cancer, fibrosis, and autoimmune disorders.
Understanding the function of TGFB1 at the molecular level is essential for developing targeted therapies for these conditions.With its high reactivity and specificity, the TGFB1 Polyclonal Antibody enables accurate detection and analysis of TGFB1 protein in a variety of cell types, making it an indispensable tool for researchers in the fields of immunology, cancer biology, and developmental biology. By providing insight into the role of TGFB1 in health and disease, this antibody contributes to the advancement of scientific knowledge and the development of novel therapeutic strategies.
Product Name:
TGFB1I1 Rabbit Polyclonal Antibody
SKU:
CAB8459
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-220 of human TGFB1I1 (NP_001035919.1).
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7041
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse lung, using TGFB1I1 antibody (CAB8459) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
