The TGFA Polyclonal Antibody (CAB0337) is a valuable tool for researchers studying the transforming growth factor alpha (TGFA) protein, an important signaling molecule involved in cell growth and differentiation. This antibody, produced using rabbits, shows high reactivity with human samples and is validated for use in Western blot applications.TGFA is known for its role in various biological processes, including cell proliferation, migration, and tissue development. Researchers can use this antibody to detect and analyze the expression of TGFA in different cell types, making it an ideal choice for studies in developmental biology, cancer research, and regenerative medicine.
Understanding the function and regulation of TGFA is crucial for unraveling its involvement in diseases such as cancer, where dysregulation of cell growth signaling pathways can lead to tumor formation and progression. By utilizing the TGFA Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying TGFA-mediated cell signaling, paving the way for novel therapeutic strategies targeting this pathway.
Product Name:
TGFA Rabbit Polyclonal Antibody
SKU:
CAB0337
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-98 of human TGFA (NP_001093161.1).
Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space.
Calculated MW:
17kDa
Observed MW:
15kDa
This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7039
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TGFA antibody (CAB0337) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
