TGF beta Receptor I (TGFBR1) Monoclonal Antibody (CAB22151)
The TGF-Beta Receptor I (TGFBR1) Monoclonal Antibody is a valuable tool for researchers studying the TGF-Beta signaling pathway. TGFBR1 is a cell surface receptor that plays a key role in regulating cell growth, differentiation, and immune response. This monoclonal antibody, produced using advanced technology, is highly specific for human TGFBR1 and is suitable for use in Western blot and immunofluorescence applications.By targeting TGFBR1, researchers can gain insights into the mechanisms underlying various diseases, including cancer, fibrosis, and immune disorders.
This antibody enables the detection and analysis of TGFBR1 expression in different cell types, providing critical information for understanding disease pathways and developing targeted therapies.With its high specificity and reliability, the TGF-Beta Receptor I (TGFBR1) Monoclonal Antibody is an essential tool for advancing research in the fields of immunology, oncology, and molecular biology. Its versatility and accuracy make it a valuable asset for scientists studying TGF-Beta signaling and its implications in health and disease.
Product Name:
TGF beta Receptor I (TGFBR1) Monoclonal Antibody
SKU:
CAB22151
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TGF beta Receptor I (TGFBR1) (NP_004603.1).
Sequence:
CCNQ DHCN KIEL PTTV KSSP GLGP VELA AVIA GPVC FVCI SLML MVYI CHNR TVIH HRVP NEED PSLD RPFI SEGT TLKD LIYD MTTS GSGS GLPL LVQR T
Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction.
Calculated MW:
56kDa
Observed MW:
56kDa
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7046
Clone Number:
ARC55592
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TGF beta Receptor I (TGFBR1) antibody (CAB22151) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
