The TFPI2 Polyclonal Antibody (CAB6214) is a valuable tool for researchers studying TFPI2, a key protein involved in regulating blood coagulation and inhibiting tumor metastasis. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the TFPI2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in the fields of hemostasis and cancer research.TFPI2, also known as tissue factor pathway inhibitor-2, is a crucial player in maintaining the balance of blood clotting processes and preventing the spread of cancer cells.
Its role in inhibiting tumor invasion and angiogenesis highlights its potential as a therapeutic target for cancer treatment and management. By studying the mechanisms of TFPI2 action, researchers can gain insights into its contribution to both hemostasis and cancer progression, paving the way for the development of novel treatment strategies.
Product Name:
TFPI2 Rabbit Polyclonal Antibody
SKU:
CAB6214
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-235 of human TFPI2 (NP_006519.1).
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7980
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Human liver cancer using TFPI2 Rabbit pAb (CAB6214) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
