The TFPI Monoclonal Antibody (CAB8704) is a high-quality antibody developed for reliable detection and analysis of target proteins. TFPI is a vital regulator of blood clotting processes, playing a key role in maintaining hemostasis and preventing excessive clot formation. This monoclonal antibody, produced in rabbits, exhibits high reactivity with TFPI in human samples and is validated for use in various applications, including Western blotting. By binding to the TFPI protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an essential tool for studies in hemostasis, thrombosis, and cardiovascular research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TFPI Monoclonal Antibody
SKU:
CAB8704
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC1154
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization.
Purification Method
Affinity purification
Gene ID
7035
RRID
AB_2863591
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from BxPC-3 cells, using TFPI Rabbit mAb (CAB8704) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
