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TFE3 Rabbit Monoclonal Antibody (CAB0548)

SKU:
CAB0548
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
RCCP2
RCCX1
TFEA
bHLHe33
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TFE3 Rabbit Monoclonal Antibody
SKU:CAB0548
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 191-440 of human TFE3 (P19532).
Sequence:LQQA RRQQ VKQY LSTT LGPK LASQ ALTP PPGP ASAQ PLPA PEAA HTTG PTGS APNS PMAL LTIG SSSE KEID DVID EIIS LESS YNDE MLSY LPGG TTGL QLPS TLPV SGNL LDVY SSQG VATP AITV SNSC PAEL PNIK REIS ETEA KALL KERQ KKDN HNLI ERRR RFNI NDRI KELG TLIP KSSD PEMR WNKG TILK ASVD YIRK LQKE QQRS KDLE SRQR SLEQ ANRS LQLR IQEL ELQA QIHG LP
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:TFEA; RCCP2; RCCX1; MRXSPF; bHLHe33; TFE3
Positive Sample:NIH/3T3 cells,C6 cells,HeLa cells
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:62kDa
Observed MW:70kDa

This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:7030
Clone Number:ARC1829
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TFE3 Rabbit mAb (CAB0548) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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