| UniProt Protein Function: | TFDP3: Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase. Belongs to the E2F/DP family.Protein type: DNA-binding; Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq26.2Cellular Component: cytoplasm; nucleusMolecular Function: protein heterodimerization activityBiological Process: G1/S transition of mitotic cell cycle; regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.[provided by RefSeq, May 2010] |
| UniProt Code: | Q5H9I0 |
| NCBI GenInfo Identifier: | 74762180 |
| NCBI Gene ID: | 51270 |
| NCBI Accession: | Q5H9I0.1 |
| UniProt Secondary Accession: | Q5H9I0,Q6DK49, Q9NZ54 |
| UniProt Related Accession: | Q5H9I0 |
| Molecular Weight: | 44,967 Da |
| NCBI Full Name: | Transcription factor Dp family member 3 |
| NCBI Synonym Full Names: | transcription factor Dp family member 3 |
| NCBI Official Symbol: | TFDP3Â Â |
| NCBI Official Synonym Symbols: | DP4; CT30; HCA661Â Â |
| NCBI Protein Information: | transcription factor Dp family member 3 |
| UniProt Protein Name: | Transcription factor Dp family member 3 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 30; CT30; Hepatocellular carcinoma-associated antigen 661 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | TFDP3Â Â |
| UniProt Entry Name: | TFDP3_HUMAN |
