The TFB1M Polyclonal Antibody (CAB15231) is a valuable tool for researchers studying TFB1M, a protein involved in mitochondrial biogenesis and mRNA modification. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TFB1M protein, this antibody allows for precise detection and analysis in various cell types, making it an essential component for investigations in the fields of mitochondrial biology and RNA modification.TFB1M is a crucial player in the maintenance of mitochondrial DNA integrity and the regulation of mitochondrial gene expression.
Dysregulation of TFB1M has been linked to a variety of diseases, including neurodegenerative disorders and metabolic diseases. Research on TFB1M can provide insights into the mechanisms underlying these conditions and may lead to the development of targeted therapies.By utilizing the TFB1M Polyclonal Antibody (CAB15231), researchers can deepen their understanding of TFB1M function and its implications in disease pathology. This antibody is a reliable tool for advancing research in mitochondrial biology and RNA modification, ultimately contributing to the development of novel therapeutic approaches for a range of health conditions.
Product Name:
TFB1M Rabbit Polyclonal Antibody
SKU:
CAB15231
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-346 of human TFB1M (NP_057104.2).
The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).
Purification Method:
Affinity purification
Gene ID:
51106
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TFB1M Rabbit pAb (CAB15231) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
